Month: November 2022

After developing severe esophagitis and being prescribed life-long medications, Jimmy Minhas, a doctor and founder of GerdLi, researched and created the world’s first natural supplement to relieve heartburn and acid reflux.

SEATTLE – November 1, 2022 – (Newswire.com)

Physician-engineered GerdLi is the natural answer for people who live with acid reflux and heartburn. It’s a premium-formulated antacid that maintains gut health and allows one to get back to eating the foods one loves. For those who hate to swallow pills, GerdLi comes as a small, easy-to-swallow capsule.

People that suffer from gastroesophageal reflux disease (GERD) are left to take prescription medications and must reduce or eliminate eating spicy foods, acrid vegetables, fatty, fried foods, fruit juices, wine, coffee and soda. Even large meals or eating before bedtime can cause uncomfortable acid reflux symptoms and, at times, damage to the esophagus.

GerdLi contains D-limonene, derived from the rinds of citrus fruits such as oranges, mandarins, lemons, limes and grapefruits and works in several ways to help with GERD.

• D-limonene decreases stomach acid
• It relieves symptoms of GERD, including indigestion, sour taste, regurgitation and bloating
• GerdLi is made with non-GMO ingredients, is vegan, gluten-free and has no artificial flavors or fillers

“So many products on the market aiming to combat GERD and acid reflux, but GerdLi is by far the best remedy I’ve used. GerdLi offers great relief and the fact that it’s created by doctors makes it stand out even more.” MK, Happy Customer

GerdLi was developed over three years, and after three months of trials and testing, half the participants found improvement in their GERD symptoms. GerdLi may work as soon as one week and averages 2-4 weeks for relief of acid reflux symptoms. One study showed 72% of the participants experienced improvement within the 2-4 week period. 

Although GerdLi is proven to alleviate heartburn and symptoms of GERD, lifestyle changes are just as crucial to a successful acid reflux regimen. GerdLi is meant to complement healthy lifestyle habits allowing patients to choose a natural way to relieve acid reflux and heartburn. Improved health includes staying active, eating clean foods and staying hydrated by drinking lots of water throughout the day. 

GerdLi is manufactured in a special FDA-registered facility, ensuring it’s a safe supplement made with the highest quality ingredients. High-potency D-limonene is carefully sourced to be sure each bottle of GerdLi delivers the most effective results for reducing acid reflux. It works as an alkaline in the stomach to reduce acid, and its name is derived from lemon rinds, which have the highest concentration of limonene.

Once D-limonene is taken, it’s rapidly absorbed in the gastrointestinal tract and distributed into tissue. GerdLi reduces heartburn and reflux symptoms and may help some people reduce the amount of prescription medication they take. 

The mission at GerdLi is to help people suffering from acid reflux while offering them an alternative to prescription medications that often cause side effects. GerdLi also cares about creating a healthier world, donating part of its proceeds to support the Esophageal Cancer Society. 

Contact Information:

Matt Kane

Media manager
[email protected]

680 850 3345

Press Release Service
by
Newswire.com

Original Source:

GerdLi: New Supplement for Heartburn Was Made by a Physician Who Sought Natural Heartburn Relief

Additional capabilities help offer higher quality, increased efficiency and more accessible, satisfying healthcare

TORONTO …

As published in the journal Food and Chemical Toxicology, the biopharmaceutical drug development firm’s sponsored research used co-cultured human, primary immune cells as a model to evaluate the ability of selected Cannabis constituents to decrease inflammation.

Gb Sciences

LAS VEGAS – November 1, 2022 – (Newswire.com)

Gb Sciences, Inc. (OTCQB:GBLX), a leading plant-inspired, biopharmaceutical research and drug development company, has co-published a study in the journal Food and Chemical Toxicology that demonstrates the potential of selected cannabinoids and terpenes to reduce inflammation. Finding Cannabis compounds with anti-inflammatory properties may be useful in decreasing inflammation associated with a wide range of serious human disorders, and these Cannabis compounds potentially have more favorable side effect profiles than NSAIDs (Non-Steroidal Anti-Inflammatory Drugs), which currently lead the anti-inflammatory market based on sales. Largely because of the increasing prevalence of chronic and auto-immune inflammatory disorders, the market for anti-inflammatory therapies is expected to grow to $191.42 billion by 2027.

“We believe that this is the first demonstration of the anti-inflammatory potential of some very potent minor cannabinoids and terpenes derived from Cannabis,” said Dr. Andrea Small-Howard, President, Chief Science Officer, and Director of Gb Sciences. “The identification of cell type-specific immune modulating effects by different individual cannabinoids and terpenes was an important first step in designing our novel anti-inflammatory therapies. The results from our second study on the anti-inflammatory effects of proprietary mixtures of these ingredients will be published subsequently with our collaborators at Michigan State University and Chaminade University.”

Gb Sciences selected the specific Cannabis constituents for this study based on their prior activity within chemovar studies. To determine whether these cannabinoids and terpenes could reduce inflammation, Gb Sciences’ colleagues at Michigan State University tested the individual Cannabis constituents over a wide range of concentrations in human, primary immune cells in a co-culture system that mimics the complex interactions that regulate the human immune system. Three immune cell types were chosen as representatives within these native human immune cell mixtures based on their important roles in modulating the inflammatory cascade.

This study demonstrated that delta-9 tetrahydrocannabinol (THC) had the greatest effect on reducing inflammatory biomarkers and processes in all three immune cell types. Following THC, the greatest immune activity modulation was measured by cannabidivarin (CBDV), cannabigerol (CBG), cannabichromene (CBC), cannabinol (CBN), and lastly, cannabidiol (CBD) in decreasing order based on the number of statistically significant changes measured in inflammatory bioassays relative to the control. Some of these minor cannabinoids and the terpenes tested had very ‘selective’ anti-inflammatory effects, which targeted a single cell type and/or caused a change in only a single inflammatory bioassay.

This study entitled “Evaluation of the anti-inflammatory effects of selected cannabinoids and terpenes from Cannabis Sativa employing human primary leukocytes” was co-authored by Gb Sciences’ own President and Chief Science Officer, Andrea Small-Howard, and her collaborators Lance K. Blevins, Anthony P. Bach, Robert B. Crawford, Jiajun Zhou, Joseph E. Henriquez, Michael D. Rizzo, Sera Sermet, D.M. Isha Olive Khan, and Norbert Kaminski from Michigan State University (East Lansing, Michigan, USA) and Helen Turner from Chaminade University of Honolulu (Honolulu, Hawai’i, USA). The second part of this study measured the effects of proprietary mixtures of cannabinoids and terpenes on inflammation within this human, primary immune cell model, and this second study will be published next in collaboration with our colleagues at Michigan State University and Chaminade University.

To learn more about Gb Sciences, visit www.gbsciences.com.

About Gb Sciences and GbS Global Biopharma

Gb Sciences, Inc. is a plant-inspired, biopharmaceutical research and development company creating patented, disease-targeted formulations of cannabis- and other plant-inspired therapeutic mixtures for the prescription drug market through its Canadian subsidiary, GbS Global Biopharma, Inc. The ‘plant-inspired’ active ingredients in its therapeutic mixtures are synthetic homologues identical to the original plant compounds but produced under current Good Manufacturing Practices. Gb Sciences’ intellectual property portfolio contains six issued U.S. and three issued foreign patents, as well as 17 U.S. and 51 foreign patent-pending applications. In its drug development pipeline, Gb Sciences has five preclinical phase product development programs. Gb Sciences’ lead program for Parkinson’s disease is being prepared for a first-in-human clinical trial. Gb Sciences’ formulations for chronic pain, anxiety, and depression are currently in preclinical animal studies with researchers at the National Research Council of Canada. The company also received positive preclinical proof-of-concept data supporting its complex mixtures for the treatment of Cytokine Release Syndrome related to COVID-19, and its lead candidates will be optimized based on late-stage preclinical studies at Michigan State University. Gb Sciences’ productive research and development network includes distinguished universities, hospitals, and Contract Research Organizations. To learn more, visit www.gbsciences.com.

Forward-Looking Statements

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Contact Information:

Madeleine Moench
[email protected]

Press Release Service
by
Newswire.com

Original Source:

Gb Sciences Co-Publishes Study Demonstrating Anti-Inflammatory Properties of Cannabis Ingredients